Re: [igraph] randomize network with more controls

[Qunawei Zhang]

Thanks. Is there a function, by which I can rewire two selected edges?

Best
Quanwei

On 9/3/15 3:38 PM, "Tamas Nepusz" <address@hidden> wrote:

>Hi,
>
>There is no built-in function for this in igraph; you'll have to
>implement the rewiring process yourself.
>
>T.
>T.
>
>
>On Thu, Sep 3, 2015 at 6:25 PM, Qunawei Zhang <address@hidden>
>wrote:
>> Hello:
>>
>> I know how to use rewire and deSeq to randomize a network and keep the
>> degree of the nodes.
>> I have a protein-protein interaction network (192 nodes and 561 edges).
>> Unlike other protein-protein interaction network, I found the
>>interactions
>> among hubs are not suppressed. I want to test whether this topology will
>> make the subnetwork more vulnerable for random attacks.
>> So  I need some random network for comparison. To randomize the network
>>I
>> want to reduce the interactions among hub genes and on the other hand
>> increase the number of interactions among hubs and non hubs. Is it
>>possible
>> to used some existing method in igraph to get this?
>>
>> Many thanks
>>
>> Best
>> Quanwei
>>
>>
>>
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>
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