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Re: [igraph] randomize network with more controls
From: |
Tamas Nepusz |
Subject: |
Re: [igraph] randomize network with more controls |
Date: |
Thu, 3 Sep 2015 21:38:37 +0200 |
Hi,
There is no built-in function for this in igraph; you'll have to
implement the rewiring process yourself.
T.
T.
On Thu, Sep 3, 2015 at 6:25 PM, Qunawei Zhang <address@hidden> wrote:
> Hello:
>
> I know how to use rewire and deSeq to randomize a network and keep the
> degree of the nodes.
> I have a protein-protein interaction network (192 nodes and 561 edges).
> Unlike other protein-protein interaction network, I found the interactions
> among hubs are not suppressed. I want to test whether this topology will
> make the subnetwork more vulnerable for random attacks.
> So I need some random network for comparison. To randomize the network I
> want to reduce the interactions among hub genes and on the other hand
> increase the number of interactions among hubs and non hubs. Is it possible
> to used some existing method in igraph to get this?
>
> Many thanks
>
> Best
> Quanwei
>
>
>
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