I'm new to this mailing list and I'm sorry if there are more threads on this that I wasn't able to find but I've been using byobu for a while now and I'ts an essential part of my remote workflow.
I am using ubuntu 14.04, I was using byobu 5.77 and I encountered this bug:
http://savannah.gnu.org/bugs/?42178 the post on the page says that there is a fix in 5.78 so I upgraded using the byobu ppa here:
https://launchpad.net/~byobu/+archive/ppa and installed 5.80 after purging old version. However the bug still persists for me. If there's an available work around or a patched version please let me know.