[Date Prev][Date Next][Thread Prev][Thread Next][Date Index][Thread Index]
Re: fitting functions which contain 'i': more details
From: |
Harbinson, Jeremy |
Subject: |
Re: fitting functions which contain 'i': more details |
Date: |
Fri, 6 Feb 2009 17:20:27 +0100 |
Hi,
The function I need to fit is one that describes the frequency dependence of
the electrical impedance (Z) of biological tissue in terms of four parameters:
capacitance,
two limiting resistances, and
alpha, which basically compensates for the fact that biological materials do
not behave as ideal Resistor-Capacitor systems.
It is difficult to clearly write the function here as it has lots of subscripts
etc, but here is the function in Latex:
Z\left(freq\right)=R_{\infty}+\frac{R_{0}-R_{\infty}}{1+i\omega
C\left(R_{0}-R_{\infty}\right)^{\alpha}}
C is capacitance, and R0 and Rinfinity are the limiting resistances.
If C is non-zero the function returns an complex number that contains the real
and imaginary parts of the impedance. If the real and imaginary parts of the
impedance are plotted against each other (real on x, imaginary on y) the result
is a so-called Cole-Cole plot. I think it is also sometimes called a Nyquist
diagram.
The data I collect is the complex impedance (Z) as a function of frequency
(omega). I would like to estimate the parameters R0, Rinfinity, C and alpha
from this data by the fitting the above function to it. So I need some fitting
tool that is happy working with complex numbers. I have a recollection that
this is/was possible with a function in the basic Matlab package, but I do not
know which.
An alternative approach to fitting the function above is to fit the Cole-Cole
plot (the real and imaginary components plotted against each other) with a
circle, as the locus of the points on a Cole-Cole plot is a chord or semicircle
whose centre is shifted away from the origin of the graph. Problems with this
approach are that the least-squares fitting routine does not (so far as I know)
fit parametric equations (maybe fsolve does?) and real data often deviates from
the chord/semicircle of the ideal Cole-Cole plot (typical biology - we are not
ideal). These distorted responses are relatively easy to deal with by tweaking
the basic function shown above, but not so easy to work with via the graphical
approach of the Cole-Cole plot.
Hope this clarifies things a bit,
all the best,
Jeremy
- Re: fitting functions which contain 'i': more details,
Harbinson, Jeremy <=